Science-Led Ventures
We partner with institutions to translate research into scalable ventures — applying scientific rigor to problems that have resisted conventional approaches for decades.
Three Nations Ventures, LLC
Venture builders helping institutions rethink stubborn challenges — combining rigorous science with cross-border collaboration.
Born from the shared values of Chile, Argentina, and the United States, we blend rich cultures and common purpose into one practice focused on progress that lasts.
Our Promise
Every program combines financial rigor with evidence-based thinking — we challenge conventional assumptions, stress-test novel approaches, and build only on what the science actually supports.
We partner with institutions to translate research into scalable ventures — applying scientific rigor to problems that have resisted conventional approaches for decades.
Our strong focus on AI-native workflows, trustworthy agents, and unified data platforms helps teams move from prototype to production with confidence.
We close the gap between Latin American entrepreneurship talent and US vision and capital — connecting founders, operators, and investors across borders to build ventures neither side could launch alone.
How we work
Deep research and scientific due diligence surface the real constraints and hidden opportunities — challenging what everyone assumes before capital is committed.
Cross-functional venture teams ship iterative releases—product strategy, engineering, and go-to-market stay in the same loop.
Continuous evidence reviews and stakeholder feedback loops ensure every venture keeps learning — validating new solutions against real-world results.
Research, field notes, and founder perspectives from the TNV network.
A field guide to replicating distributed network models that have outperformed centralized approaches in rural Latin America.
March 2026How two portfolio companies are applying cell-agriculture science to long-standing bottlenecks in cross-border distribution and cold-chain logistics.
February 2026Examining how evidence-led regulatory approaches help founders navigate divergent US and LatAm frameworks without slowing down R&D.
January 2026Share your priorities and we'll outline the research, technology, and capital needed to move from idea to implementation.
Tell us about your venture, partnership idea, or investment request.
Whether you're a founder seeking capital, an LP exploring allocations, or a partner with aligned mission — we'd like to hear from you. Expect a reply within two business days.